Why and how to go gluten-free

With the proliferation of gluten-free products and a host of similar-sounding medical conditions, there’s a lot of confusion about gluten these days.

Now that it’s trendy to eliminate gluten from your diet, those with an actual medical condition may be overlooked. If you’ve been diagnosed with celiac disease, non-celiac gluten sensitivity, or a wheat allergy, you may have a number of questions.

What makes your condition unique from others? What are the foods you can and can’t eat — and why?

Even without a medical condition, you may have wondered if removing gluten from your diet is good for general health.

Here’s a comprehensive look at these conditions, who needs to limit or avoid gluten, and what exactly that means for day-to-day food choices.

What is gluten and who needs to avoid it?

In simple terms, gluten is a name for a group of proteins found in grains like wheat, barley, and rye — they add elasticity and chewiness to breads, baked goods, pastas, and other foods.

For most people, there’s no health reason to avoid gluten. The theories that gluten promotes weight gain, diabetes, or thyroid dysfunction haven’t been confirmed in medical literature.

In fact, a diet that includes whole grains (many of which contain gluten) is associated with numerous positive outcomes, like reduced risk of heart diseaseTrusted Sourcetype 2 diabetesTrusted Source, and colon cancerTrusted Source.

However, there are health conditions that require limiting or removing gluten and foods containing gluten from the diet: celiac disease, wheat allergy, and non-celiac gluten sensitivity.

Each comes with differences in symptoms — some subtle and some dramatic — as well as different dietary restrictions. Here’s what you need to know:

Celiac disease

Celiac disease is an autoimmune disorder that affects around 1 percentTrusted Source of Americans, though more may be undiagnosed.

When people with celiac disease eat gluten, it triggers an immune response that damages their small intestine. This damage shortens or flattens the villi — absorbent finger-like projections that line the small intestine. As a result, the body can’t properly absorb nutrients.

There’s currently no other treatment for celiac disease except the complete exclusion of gluten. Therefore, people with this condition must be vigilant about eliminating all gluten-containing foods from their diet.

Symptoms of celiac disease

  • diarrhea
  • constipation
  • vomiting
  • acid reflux
  • fatigue

Some people report mood changes like a feeling of depression. Others don’t experience any obvious symptoms in the short-term.

“About 30 percent of people with celiac don’t have the classic gut symptoms,” says Sonya Angelone, RD, spokesperson for the Academy of Nutrition and Dietetics. “So they may not get checked or diagnosed.” In fact, research indicates that the majority of people with celiac disease don’t know they have it.

Left untreated, celiac disease can lead to serious health issues in the long-term, such as:

Complications of celiac disease

  • anemia
  • infertility
  • vitamin deficiencies
  • neurological problems

Celiac disease is also commonly related to other autoimmune conditions, so someone with celiac disease has a higher risk of developing a concurrent disorder that attacks the immune system.

Doctors diagnose celiac disease in one of two ways. First, blood tests can identify antibodies that indicate an immune reaction to gluten.

Alternatively, the “gold standard” diagnostic test for celiac disease is a biopsy conducted via endoscopy. A long tube gets inserted into the digestive tract to remove a sample of the small intestine, which can then be tested for signs of damage.

Foods to avoid for celiac disease

If you’ve been diagnosed with celiac disease, you’ll need to avoid all foods that contain gluten. This means all products that contain wheat.

Some common wheat-based products include:

  • bread and bread crumbs
  • wheat berries
  • wheat tortillas
  • pastries, muffins, cookies, cakes, and pies with wheat crust
  • wheat-based pastas
  • wheat-based crackers
  • cereals that contain wheat
  • beer
  • soy sauce

Many grains that don’t have wheat in their name are actually variants of wheat and must also stay off the menu for people with celiac disease. These include:

  • couscous
  • durum
  • semolina
  • einkorn
  • emmer
  • farina
  • farro
  • kamut
  • matzo
  • spelt
  • seitan

Several other grains besides wheat contain gluten. They are:

  • barley
  • rye
  • bulgur
  • triticale
  • oats processed in the same facility as wheat
Wheat allergy

wheat allergy is, quite simply, an allergic reaction to wheat. Like any other food allergy, an allergy to wheat means that your body creates antibodies to a protein that wheat contains.

For some people with this allergy, gluten may be the protein that causes an immune response — but there are several other proteins in wheat that could also be the culprit, such as albumin, globulin, and gliadin.

Symptoms of wheat allergy

  • wheezing
  • hives
  • tightening in the throat
  • vomiting
  • diarrhea
  • coughing
  • anaphylaxis

Because anaphylaxis can be life-threatening, people with a wheat allergy should carry an epinephrine autoinjector (EpiPen) with them at all times.

Approximately 2 million U.S. adultsTrusted Source have a wheat allergy, but it’s most common in children, affecting around 3 percentTrusted Source. Two thirds of kids with a wheat allergy outgrow it by age 12.

Doctors use various tools to diagnose a wheat allergy. In a skin test, wheat protein extracts are applied to pricked skin on the arms or back. After about 15 minutes, a medical professional can check for allergic reactions, which appear as a raised red bump or “wheal” on the skin.

A blood test, on the other hand, measures antibodies to wheat proteins.

However, since skin and blood tests yield a false positive 50 to 60 percent of the time, food journals, diet history, or an oral food challenge are often necessary to determine a true wheat allergy.

An oral food challenge involves consuming increasing amounts of wheat under medical supervision to see if or when you have an allergic reaction. Once diagnosed, people with this condition need to steer clear of all wheat-containing foods.

Foods to avoid with wheat allergy

People with a wheat allergy must be extremely careful to eliminate all sources of wheat (but not necessarily all sources of gluten) from their diet.

Not surprisingly, there’s a lot of overlap between the foods people with celiac disease and wheat allergy must avoid.

Like those with celiac disease, people with wheat allergy shouldn’t eat any of the wheat-based foods or grain variants of wheat listed above.

Unlike those with celiac disease, however, people with wheat allergy are free to eat barley, rye, and wheat-free oats (unless they have a confirmed co-allergy to these foods).

Non-celiac gluten sensitivity (NCGS)

While celiac disease and wheat allergy have a long history of medical recognition, non-celiac gluten sensitivity (NCGS) is a relatively new diagnosis — and it hasn’t been without controversy, since symptoms of NCGS may be vague or unrepeatable from one gluten exposure to the next.

Still, some experts estimate that up to 6 percentTrusted Source of the population is gluten-sensitive — a far higher percentage of the population than those who have celiac disease or wheat allergy.

Symptoms of non-celiac gluten sensitivity

  • bloating
  • constipation
  • headaches
  • joint pain
  • brain fog
  • numbness and tingling in the extremities

These symptoms can appear within hours, or may take days to develop. Due to lack of research, long-term health implications of NCGS are unknown.

Research has yet to pinpoint the mechanism that causes NCGS. It’s clear that NCGS doesn’t damage villi or cause harmful intestinal permeability. For this reason, someone with NCGS won’t test positive for celiac disease, and NCGS is considered a less severe condition than celiac.

There’s no single accepted test for diagnosing NCGS. “A diagnosis is based on symptoms,” says dietitian Erin Palinski-Wade, RD, CDE.

“Although some clinicians will use testing of saliva, stool, or blood to identify sensitivities to gluten, these tests have not been validated, which is why they are not accepted as official ways to diagnosis this sensitivity,” she adds.

As with a wheat allergy, keeping track of food intake and any symptoms in a journal may prove useful for identifying NCGS.

Foods to avoid with non-celiac gluten sensitivity

A diagnosis of non-celiac gluten sensitivity does call for completely removing gluten from the diet, at least temporarily.

To minimize uncomfortable symptoms, someone with NCGS should stay away from the same list of foods as someone with celiac disease, including all wheat products, wheat variants, and other gluten-containing grains.

Fortunately, unlike celiac disease, an NCGS diagnosis may not last forever.

“If someone can decrease their overall stress on their immune system by eliminating other foods or chemicals that are eliciting an immune response, then they may be able to eventually reintroduce gluten in small or normal amounts,” says Angelone.

Palinski-Wade says that, for people with NCGS, paying attention to symptoms is key to determining how much gluten they can eventually reintroduce.

“Using food journals and elimination diets along with the tracking of symptoms, many individuals with gluten sensitivity can find a level of comfort that works best for them,” she says.

If you’ve been diagnosed with NCGS, work with a doctor or dietitian who can supervise the process of eliminating or adding back foods to your diet.


As many people on a gluten-free diet have discovered, steering clear of gluten isn’t as easy as cutting out breads and cake. A number of other foods and non-food substances are surprising sources of these ingredients. Be aware that gluten or wheat may be hiding in unexpected places, such as the following:

Potential gluten- and wheat-containing foods:

  • ice cream, frozen yogurt, and pudding
  • granola or protein bars
  • meat and poultry
  • potato chips and french fries
  • canned soups
  • bottled salad dressings
  • shared condiments, like a jar of mayonnaise or tub of butter, which may lead to cross-contamination with utensils
  • lipsticks and other cosmetics
  • medications and supplements

Keywords to watch for

Processed foods are often enhanced with additives, some of which are wheat-based — even though their names might not appear so.

A number of ingredients are “code” for wheat or gluten, so savvy label reading is essential on a gluten-free diet:

  • malt, barley malt, malt syrup, malt extract, or malt flavoring
  • triticale
  • triticum vulgare
  • hordeum vulgare
  • secale cereal
  • hydrolyzed wheat protein
  • graham flour
  • brewer’s yeast
  • oats, unless specifically labeled gluten-free

Many companies are now adding a “certified gluten-free” label to their products. This stamp of approval means the product has been shown to contain less than 20 parts of gluten per million — but is entirely optional.

Although it’s required to state certain allergens in food, the FDA doesn’t require food producers to state that their product contains gluten.

When in doubt, it’s a good idea to check with the manufacturer to confirm whether a product contains wheat or gluten.

Smart swaps | Smart Swaps

Navigating breakfast, lunch, dinner, and snack time without gluten can be challenging, especially at first. So what can you actually eat? Try replacing some of these common food items with their gluten-free alternatives.

Instead of: Try:
wheat pasta as a main dish gluten-free pasta made with chickpea, rice, amaranth, black bean, or brown rice flour
pasta or bread as a side dish rice, potatoes, or a gluten-free grains like amaranth, freekeh, or polenta
couscous or bulgur quinoa or millet
wheat flour in baked goods almond, chickpea, coconut, or brown rice flour
wheat flour as a thickener in puddings, soups, or sauces cornstarch or arrowroot flour
brownies or cake pure dark chocolate, sorbet, or dairy-based desserts
cereal made with wheat cereals made with rice, buckwheat, or corn; gluten-free oats or oatmeal
soy sauce tamari sauce or Bragg’s amino acids
beer wine or cocktails
Last word

Removing wheat or gluten from your diet is a major lifestyle change that may seem overwhelming at first. But the longer you practice making the right food choices for your health, the more it will become second nature — and, quite likely, the better you’ll feel.

Remember to always consult with a health professional before you make any major changes to your diet or if you have any questions about your individual health.


Medically reviewed by Natalie Olsen, RD, LD, ACSM EP-C on June 21, 2019 — Written by Sarah Garone